Faculty Profile - Zoran Gatalica , M.D., D.Sc.

Zoran Gatalica , M.D., D.Sc.
Director, Anatomic Pathology

Creighton University Medical Center
Pathology Department and
Creighton Medical Laboratories
601 N. 30th St.
Omaha, NE. 68131-2197
Phone: (402) 280-4858
ZoranGatalica@creighton.edu
  • Director, Surgical Pathology
  • Pathologist, Creighton University Medical Center and Omaha Veterans Hospital
  • Professor of Pathology

Education

  • M.D. - School of Medicine, University of Zagreb, Croatia (1984)
  • D.Sc. - School of Natural Sciences, University of Zagreb, Croatia (1989)
  • Postdoctoral Research Fellow in Pathology, Thomas Jefferson University, Philadelphia, PA. (1990-1992)
  • Resident in Pathology (AP/CP), Thomas Jefferson University Hospital, Philadelphia, PA. (1992-1996)
  • Chief Resident, Thomas Jefferson University Hospital, Philadelphia, PA. (1995-1996)

Certifications

  • E. C. F. M. G. Examination (Jan 1990)
  • Federal Licensing Examination, PA (Dec 1990)
  • The American Board of Pathology Certification in Anatomic and Clinical Pathology (June 1997)

Publications

  • Zoran Gatalica, Gopalrao Velagaleti, Helena Kuivaniemi, Gerard Tromp, Juan Palazzo, Kerry M. Graves, Michelle Guigneaux, Thomas Wood, Mala Sinha, and Bruce Luxon (2005): Gene expression profile of an adenomyoepithelioma of the breast with a reciprocal translocation involving chromosomes 8 and 16 [46, XX,t(8;16)(p23;q21)]. Cancer Genetics Cytogenetics 156:14-22
  • Caughron SK, Bridge JA, Bewtra CB, Hunter WJ, Nelson M, Soundararajan, Silva E and Gatalica Z (2005): Monosomy 22 as a diagnostic aid in a case of late recurrence of adult granulosa cell tumor of the ovary. Cancer Genetics Cytogenetics 156:83-85
  • C Bewtra, Q Xie, S Soundararajan, Z Gatalica, L Hatcher (2005): Genital Human Papilloma Virus testing by In-situ Hybridization Method in Liquid Prepared Atypical Cytologic Materials and Follow up Biopsies. Acta Cytologica 49; 2:127-131
  • Gao X, Mohsin SK, Gatalica Z, Fu G, Sharma P, Nawaz Z (2005): Decreased expression of E6-AP in breast and prostate carcinomas. Endocrinology 146;4:1707-1712
  • Gatalica Z and Bing Z (2005): Syk tyrosine kinase expression during multistep mammary carcinogenesis. Croat Med J 46(3):372-376
  • Gokhale S, Gatalica Z, Mohammad A, Rampy A and Velagaleti G (2004): FISH for HER-2neu in breast cancer, Standardization makes the difference! Indian J Cancer; 41(4):152-8.
  • Reynoso J, Davis RE, Daniels WW, Awad ZT, Gatalica Z, Filipi CJ (2004). Esophageal papillomatosis complicated by sqaumos cell carcinoma in situ. Dis Esophagus. 2004; 17(4):345-7.
  • Sheng T, Li C, Zhang X, Chi S, He N, Chen K, McCormick F, Gatalica Z, Xie J (2004): Activation of hedgehog pathway in advanced prostate cancer. Molecular Cancer 3:29-41
  • Tromp G, Gatalica Z, Skunca M, Berguer R, Siegel T, Kline RA, Kuivaniemi H (2004): Elevated expression of matrix metalloproteinase-13 in abdominal aortic aneurysms. Ann Vasc Surg 18:414-420
  • Murray NR, Jamieson L, Yu W, Zhang J, Gokmen-Polar Y, Sier D, Anastasidis P, Gatalica Z, Thompson EA, Fields AP (2004): Protein kinaseC is required for ras transformation and colon carcinogenesis in vivo. J Cell Biol 164:797-802.
  • Velagaleti GV, Miettinen M and Gatalica Z (2004): Malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation (malignant triton tumor) with reciprocal translocation (7;9)(q11.2;p24) and unbalanced translocation der (16)t(1;16)(q23;q13). Cancer Genetics Cytogenetics 049:23-27
  • Haeberle, H., Casola, A., Gatalica, Z., Petronella S., Dieterich, H.-J., Ernst, P.B., Braiser, A.R., Garofalo, R.P (2004): The IkB kinase is a critical regulator of chemokine expression and lung inflammation in respiratory syncytial virus infection. J Virol 78:2232-2241
  • Lynch HT, Deters CA, Hogg D, Lynch JF, Kinarsky J, and Gatalica Z: Familial sarcoma: Challenging pedigrees. Cancer 2003; 98:1947-57
  • Popnikolov NK, Ayala AG, Graves K, and Gatalica Z (2003): Benign myoepithelial tumors of the breast have immunophenotypical characteristics similar to metaplastic matrix producing and spindle cell carcinomas. Am J Clin Pathol 120:161-167
  • Ge Y, Gatalica Z, Xiao SY (2003): Pathologic Quiz Case: Right Thigh Pain for 14 Months. Arch Pathol Lab Med 127(3):e171-e172
  • Popnikolov NK, Gatlica Z, Colome-Grimmer MI, and Sanchez RL (2003): Loss of mismatch repair proteins in sebaceous gland tumors. Journal of Cutaneous Pathology 30:178-184.
  • Haeberle HA, Takizawa R, Casola A, Brasier AR, Dietrich HJ, van Rooijn N, Gatalica Z and Garofalo RP (2002): Respiratory syncytial virus-induced activation of NF-kappa B in the lung involves alveolar macrophages and Toll-like receptor 4-dependent pathways. J Infect Dis 186:1199-206.
  • Velagaleti GVN, Tapper JK, Panova NE, Miettinen M, and Gatalica Z (2002): Cytogenetic findings in a case of nodular fasciitis of subclavicular region. Cancer Genet Cytogen (in press)
  • Wang Q, Wang X, Hernandez A, Hellmich MR, Gatalica Z, and Evers BM (2002): Regulation of TRAIL expression by the PI3-kinase/Akt/GSK-3 pathway in human colon cancer cells. J Biol Chem, 277:36602-36610.
  • Yoon S, Kuivaniemi H, Gatalica Z, Olson JM, Buttice G, Ye S, Norris BA, Malcolm GT, Strong JP, and Tromp G (2002): MMP13 promoter polymorphism is associated with atherosclerosis in the abdominal aorta of young black males. Matrix Biology, 21:487.
  • Eyzaguirre E and Gatalica Z (2002): Loss of Fhit expression in testicular germ cell tumors and intratubular germ cell neoplasia. Modern Pathology, 15:1068-1072.
  • Lele SM, Pou AM, Ventura K, Gatalica Z, Payne D (2002): Molecular events in the progression of recurrent respiratory papillomatosis to carcinoma. Arch Pathol Lab Med, 126:1184-1188.
  • Haeberle HA, Nesti F, Dieterich HJ, Gatalica Z, Garofalo R (2002): Perflubron reduces lung inflammation in respiratory syncitial virus infection by inhibiting chemokine expression and NF-kB activation. Am J Resp Crit Care Med 165:1433-1438
  • Filipowicz E, Adegboyega P, Sanchez R, and Gatalica Z (2002): Expression of CD95 (Fas) in sun-exposed human skin and cutaneous carcinomas. Cancer 94(3): 814-819
  • Diaz-Arrastia C, Arany I, Robazetti SC, Dinh TV, Gatalica Z, Tyring SK, Hannigan E (2001): Clinical and molecular responses in high grade intraepithelial neoplasia treated with topical Imiquimod 5%. Clin Cancer Res 7: 3031-3033
  • Saitoh Y, Pasricha PJ, West AB, Popnikolov NK, Gatalica Z, Watari J, Obara T, Kohgo Y, and Waxman I (2001): Prevalence and distinctive biological features of flat colorectal adenomas in a North American population. Gastroenterology 120:1657-1665.
  • Sovani V, Velagaleti GVN, Filipowicz E, Gatalica Z and Knisely AS (2001) Ossifying fibromyxoid tumor of soft parts - report of a case with novel cytogenetic findings. Cancer Gen Cytogen 127:1-6.
  • Gatalica Z, Finkelstein S, Lucio E, Tawfik O, Palazzo J, Hightower B and Eyzaguirre, E (2001) P53 protein expression and gene mutation in phyllodes tumors of the breast. Pathol Res Pract 197(3):183-187.
  • Gokmen-Polar Y, Murray NR, Velasco MA, Gatalica Z and Fields, AP (2001) Elevated protein kinase C bII is an early promotive event in azoxymethane (AOM)-induced mouse colon carcinogenesis. Cancer Res 61:1375-1381.
  • Haeberle H, Kuziel WA, Dieterich HJ, Casola A, Gatalica Z, and Garofalo RP (2001): Inducible expression of inflammatory chemokines in respiratory syncytial virus-infected mice: Role of MIP-1a in lung pathology. J Virol 75:878-890
  • Miettinen M, Fernandez M, Franssila K, Gatalica Z Lasota J and Sarlomo-Rikala M (2001): Microphthalmia Transcription Factor in the Immunohistochemical Diagnosis of Metastatic Melanoma - Comparison with Four Other Melanoma Markers. Am J Surg Pathol 25:205-211
  • Gatalica Z (2000): Metallothionein Expression in Normal Male Genitourinary Tract and Corresponding Neoplasms. J Urol Pathol 12(3): 169-178
  • Gaa Z, Kovatich AJ, and Norris BA (2000): Immunohistochemical localization of prostate specific antigen in ductal epithelium of male breast: A potential pitfall in patients with gynecomastia. Applied Immunohistochem Molec Morphol 8:158-161
  • Lele SM, Graves KM, and Gatalica Z (2000): Immunohistochemical detection of maspin is a useful adjunct in distinguishing radial sclerosing lesion from tubular carcinoma of the breast. Applied Immunohistochem Molec Morphol 8:32-36
  • Diaz de Leon E, Carcangiu ML, Prieto VG, McCue PA,. Burchette JL, Kovatich A, To G, Sanchez RL, Krigman HR and Gatalica Z, (2000): Extramammary Paget’s disease is characterized by consistent lack of expression of estrogen and progesterone receptors but frequently expresses androgen receptor. Am J Clin Path 113:572-575
  • Schnadig VJ, Adesokan A, Neal D, and Gatalica Z (2000): Urinary cytologic findings in patients with benign and malignant adenomatous polyps of the prostatic urethra. Arch Pathol Lab Med 124:1047-1052
  • Eyzaguirre EJ, Miettinen M, Norris BA, and Gatalica Z (1999): Different immunohistochemical patterns of Fhit protein expression in renal neoplasms. Mod Pathol 12:979-983.
  • Gatalica Z, Wang L , Lucio E and Miettinen M (1999): Glomus coccygeum in surgical pathology specimens: Small troublemaker. Archives Pathol Lab Med, 123:905-908
  • Gatalica Z (1998): Immunohistochemical analysis of steroid hormone receptors in nasopharyngeal angiofibromas. Cancer Lett 127:89-93
  • Gatalica Z. (1997): Immunohistochemical analysis of apocrine breast lesions. Consistent over-expression of androgen receptor accompanied by the loss of estrogen and progesterone receptors in apocrine metaplasia and apocrine carcinoma in situ. Path Res Pract 193:753-758
  • Gatalica Z., Miettinen M, and McCue PA (1997): Basement membrane-like secretions form hyaline globules in renal cell carcinomas. Human Pathol 28:400-403
  • Gatalica Z., Grujic S., Kovatich A., and Petersen R.O.(1996): Metanephric adenoma. Histology, immunophenotype, cytogenetics, ultrastructure. Mod Pathol 9:329-333.
  • Kuivaniemi H., Watton S.J., Price S.J., Zhu Y., Gatalica Z., and Tromp G.(1996): Candidate Genes for Abdominal Aneurysms. Ann New York Acad Sci 800:186-197
  • Gatalica Z., Kovatich A., and Miettinen M. (1995): Consistent expression of cytokeratin 7 in papillary renal cell carcinoma. J Urol Pathol 3:205-212
  • Gatalica Z., and Miettinen M. (1994): Distribution of carcinoma antigens CA19-9 and CA 15-3: An immunohistochemical study of 400 tumors. Appl Immunohistochem 2:205-211.
  • Gatalica Z., Schwarting R. and Petersen R.O. (1994) Renal cell carcinoma in the presence of adult polycystic kidney disease. Urology 43:102-105.
  • Tromp G, Kuivaniemi H, Wu Y, Prockop DW, Madhatherti S, Kleinert C,Earley J, Zhuang J, Norrgard O, Darling RC, Abbott WM, Cole W, Jaakola P, Ryynanen M, Pearce W, Yao J, Majamaa K, Smullens S, Gatalica Z, Ferrel R, Jimenez S, Jackson C, Michels C, Kayer M. (1993): Sequencing of cDNA for the entire triple-helical domain of type III procollagen from 50 unrelated patients with aortic aneurysms reveals a mutation in obligatory Glycine in one patient. J Clin Invest 91:2539-2545
  • Gatalica Z., Moehren, G. and Hoek J.B. (1993) Unilateral nephrectomy selectively stimulates phospholipase D in the remaining kidney. Biochim Biophys Acta 1177:87-92
  • Gatalica Z., Gibas Z. and Martinez-Hernadez A. (1992) Dissecting aortic aneurysm as a complication of generalized fibromuscular dysplasia. Hum Pathol 23:586-588.
  • Gatalica Z., and Damjanov I. (1990) Effects of alcohols on mouse embryonal carcinoma- substrate adhesion. Histochemistry 95:189-193
  • Banfic H., and Gatalica Z. (1989) Plasma from uninephrectomised rats stimulates phospholipid methylation and arachidonic acid release in renal cortical slices. Biochem J 260:365-369.
  • Gatalica Z. and Banfic H. (1988) Epidermal growth factor stimulates the incorporation of phosphate into phosphatidic acid and phosphoinositides, but does not affect phosphoinositides breakdown by phospholipase C in renal cortical slices. Biochim Biophys Acta 968:379-384.