Mingkui Chen, M.D., Ph.D.
PGY 4, Chief Resident
mingkuichen@creighton.edu

Education

Research Experience

Publications

Hu Q, Popa I, Fu K, Chen M, Chan WC (2007) Clonal CD8+ lymphocytic proliferation associated by Epstein-Barr virus infection mimicking T-cell leukemia. Leuk  Lymphoma 48:1651-1653.

Mingkui Chen & Deba P. Sarma: Wooden Splinter Dermatitis: The Internet Journal of Dermatology. 2007; Volume 5, Number 2

Chen M, Gatalica Z, Wang B. Cartilaginous and osseous metaplasia in the aortic valve. The Internet J Cardiol 4(2).

Mingkui Chen & Deba P. Sarma: Intramuscular Angioma of the Frontalis Muscle: The Internet Journal of Dermatology. 2007; Volume 5, Number 2

Eric E. Santos, Deba P. Sarma, Mingkui Chen & Bo Wang: Metatypical Basal Cell Carcinoma of the Nose: The Internet Journal of Dermatology. 2007; Volume 5, Number 2.

Chen M, Sarma DP (2007). Multiple dermatofibromas in an adult female. The Internet J Dermatol 5(1)

Hu Q, Popa I, Fu K, Chen M, Chan WC (2007) EBV-induced clonal CD8+ lymphocytosis. Leuk Lymphoma (accepted).

Simard JM, Kent TA, Chen M, Tarasov KV, Gerzanich V. Molecular pathophysiology of brain edema in focal ischemia ? a focused review. Lancet Neurol Vol 6, March 2007.

Sun Y, Chen M, Lowentritt BH, Van Zijl PS, Koch KR, Keay S, Simard JM, Chai TC (2006). EGF and HB-EGF modulate inward potassium current in human bladder urothelial cells from normal and interstitial cystitis patients. Am J Physiol Cell Physiol 2006 Jul 12.

Simard JM, Chen M, Tarasov KV, Bhatta S, Ivanova S, Melnitchenko L, Tsymbalyuk N, West GA, Gerzanich V (2006) Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke. Nat Med 12: 433-440.

Simard JM, Chen M (2004) Regulation by sulfonylurea receptor type 1 of a non-selective cation channel involved in cytotoxic edema of reactive astrocytes. J Neurosurg Anesthesiol 16: 98-99.

Perillan PR, Chen M, Potts EA, Simard JM (2002) Transforming growth factor-beta 1 regulates Kir2.3 inward rectifier K+ channels via phospholipase C and protein kinase C-delta in reactive astrocytes from adult rat brain. J Biol Chem 277: 1974-1980.

Chen M, Dong Y, Simard JM (2003) Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain. J Neurosci 23: 8568-8577.

Chen M, Simard JM (2001) Cell swelling and a nonselective cation channel regulated by internal Ca2+ and ATP in native reactive astrocytes from adult rat brain. J Neurosci 21: 6512-6521.

Patents:

J. Marc Simard & Mingkui Chen. A Novel Non-selective Cation Channel in Neural Cells and Methods for Treating Brain Swelling. US Patent Application10/391,561. Publication No. US-2003-0215889-A1.

Teaching Experience

Medical School Teaching:
2008-2009	  IDC279 Case Studies in Clinical Medicine (2nd year Medical Students, 126 students)
                   Assistant moderator, clinical medicine small groups for medical students 
                  Creighton University School of Medicine

2006-2009	  PTG461 Introduction to Pathology Practice (4th year Medical Students, elective, 9 students yearly). 
                   Provide daily guidance into a broad introduction in the practice of pathology in the art of gross description,
                   microscopic evaluation and diagnosis.

2006-2009	  PTG467 Survey of Pathology Practice (4th year Medical Students, elective, 6 students yearly).  
                   Provide a broad introduction in the practice of pathology built around interaction with clinicians, pathologists,
                   residents, and technical staff. This elective is designed to offer each student an 
                   opportunity to gain an introductory understanding of the practice of clinical and anatomic pathology. 

2009-2007	  CAN640 Clinical Rotations in Surgery, Radiology, and Pathology 
                  (Graduate Students, shadow grossing procedures and techniques) 22 students, Jan – May, daily

Non-Medical School Teaching:
2007-2009    Instructor  PTG105 - Introduction to Human Disease - Physical Therapy & Pharmacy students. 
                                                 3 semester hours, 210 students, (three lectures, 1.5 hrs each)

Interdisciplinary Teaching:
• Tumor Board Interdisciplinary Patient Care Conference (weekly conference involving Surgery, Pathology, and Radiology)
      • Conduction and Presentation of Pathology Component 
• Hospital Grand Rounds Presentations
      	
Medical School Teaching (Outside Creighton):
07/1995 - 09/1998 Teaching Instructor 
Responsible for teaching second-year medical students of Medical Immunology & Microbiology and instructing labs. 
Department of Immunology & Microbiology, Nanjing University School of Medicine

Honors

7/08-07/09 Chief Resident
09/2000 American Society of Clinical Pathologists,
Regional Associate Member Award
09/1998 Bioniche International Research Award, Canada
05/1997 Excellent Teaching Award, Nanjing University, China
08/1995 Magna Cum Laude Medical Graduate, Nanjing University, China
08/1994 Baogang Scholarship Award, China

Hobbies

Fishing and Soccer